This study was performed to compare cartilage T2 between subjects with and without meniscus tears. T2 mapping was performed on the knees of 30 control subjects without meniscus tears and 93 subjects with meniscus tears. Medial and lateral compartment cartilage T2 was measured. Radiographic osteoarthritis severity was assessed using the Kellgren-Lawrence (KL) grading scale. The 30 KL-0 control subjects without meniscus tears had significantly lower (p<0.001) medial compartment cartilage T2 than KL-0 (n=46), KL 1 (n=27), and KL-2 (n=20) subjects with meniscus tears and significantly lower (p<0.01) lateral compartment cartilage T2 than KL-1 and KL-2 subjects with meniscus tears.