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Abstract #1461

T2 Relaxation in Evaluating Gd deposition: comparison between MultiHance and Magnevist

Ning HUA1, Pedro V. Staziaki2, Mohamad Assayuri2, Vanesa Carlota Andreu Arasa2, Hernan Jara1, and Osamu Sakai2

1Boston University, Boston, MA, United States, 2Boston Medical Center, Boston, MA, United States

Purpose: To evaluation quantitative T2 mapping in exploring the effects of prior Gd exposure. Methods: Dual-echo MRI was performed in three groups of subjects; 1) without prior Gd exposure history, 2) only with prior exposure to MultiHance®, and 3) only with prior exposure to Magnevist®. T2 relaxation times were measured in pons, dentate nuclei, globus pallidi and thalami. Results: T2 relaxation time decrease was observed for both contrast agents in dentate nuclei and globus pallidi. Conclusion: Quantitative T2 mapping is a valuable tool in the investigation of Gd deposition in the brain.

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