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Abstract #1488

A hardware and algorithm framework for focal spot and slice positioning in MRgFUS treatments

Robb P Merrill1, J Rock Hadley1, Katelynn R Stroth1, Dylan E Palomino1, Dennis L Parker1, and Allison H Payne1

1Utah Center for Advanced Imaging Research (UCAIR), University of Utah, Salt Lake City, UT, United States

MRgFUS systems can be designed with a high degree of transducer positioning variability for precise focal point placement during tissue ablation procedures. This study evaluates hardware design and complementary algorithmic adaptations that predict the focal spot location and MRI slice orientation as a function of transducer adjustment settings. These design features were evaluated by comparing the physical focus of a mock transducer to the computed focus location from the prediction algorithm. The mean error between the measured and predicted point position was found to be 2.9±1.8mm (N=20). Predicted slice orientation parameters also showed good agreement with hardware adjustment measurements.

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