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Abstract #1510

MRI-based radiomic to assess lipomatous soft tissue tumors malignancy: a pilot study

Benjamin Leporq1, Amine Bouhamama2, Fabrice Lame2, Catherine Bihane2, Michaël Sdika1, Jean-Yves Blay3, Olivier Beuf1, and Frank Pilleul1,2

1Laboratoire CREATIS (CNRS UMR 5220, Inserm U1206, INSA-Lyon, UCBL Lyon 1), Université de Lyon, Lyon, France, 2Department of radiology, Centre de lutte contre le cancer Léon Berard, Lyon, France, 3Department of oncology, Centre de lutte contre le cancer Léon Berard, Lyon, France

Aim of this study was to develop a MRI-based radiomic method to assess lipomatous soft tissue tumors malignancy. 105 subjects with lipomatous soft tissue tumors whose histology was known and with fat-suppressed T1w contrast enhanced MR images available were retrospectively enrolled to constitute a database. Based on histology, three groups were constituted according to malignancy from lipomas to high grade liposarcomas. A decisional algorithm based on 2 multivariate radiomic models was built to distinguish between these groups. Results demonstrate that the evaluation of lipomatous tumor malignancy is feasible using a routinely used MRI acquisition in clinical practice.

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