This study systematically investigates a fundamental question for tractogram-based connectomics research: for a given resolution of brain parcellation, how many streamlines are required for reproducible connectome construction? We incorporate state-of-the-art tractography techniques with surface parcellation schemes of multiple granularities to investigate the influence of streamline count on the connectome variability. Our results suggest that selecting an appropriate number of streamlines is crucial for global and per-edge variability of the connectome, revealing important implications for subsequent network analysis and inferences. Methods that investigate structural connectivity with different brain parcellation resolutions should benefit from the experimental workflow and outcomes of this study.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords