Abstract #1581

A method to estimate the product of perfusion fraction f and pseudodiffusion coefficient Dp of IVIM without estimating f and Dp

Eizou Umezawa¹, Masahiro Kawasaki¹, Yukiko Sonoda¹, Takashi Fukuba², Kazuhiro Murayama³, Kazuki Takano¹, Masayuki Yamada¹, Toshiyuki Onodera⁴, and Masahiro Ida⁴

¹Graduate School of Health Sciences, Fujita Health University, Toyoake, Japan, ²Department of Radiology, Fujita Health University Hospital, Toyoake, Japan, ³School of Medicine, Fujita Health University, Toyoake, Japan, ⁴Department of Radiology, Tokyo Metropolitan Health and Medical Treatment Corporation Ebara Hospital, Tokyo, Japan

IVIM analysis can provide the perfusion fraction f and the pseudodiffusion coefficient D* or D_p in addition to the diffusion parameters. The product of f and D* is known to relate to cerebral blood flow. Recently, a higher diagnostic performance of fD* than f and D* has been reported. We propose a method to estimate fD_p without estimating f and D_p using DKI analysis. The DKI based IVIM analysis can be implemented easily and provides fD_p values with a high degree of precision.

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