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Abstract #1581

A method to estimate the product of perfusion fraction f and pseudodiffusion coefficient Dp of IVIM without estimating f and Dp

Eizou Umezawa1, Masahiro Kawasaki1, Yukiko Sonoda1, Takashi Fukuba2, Kazuhiro Murayama3, Kazuki Takano1, Masayuki Yamada1, Toshiyuki Onodera4, and Masahiro Ida4

1Graduate School of Health Sciences, Fujita Health University, Toyoake, Japan, 2Department of Radiology, Fujita Health University Hospital, Toyoake, Japan, 3School of Medicine, Fujita Health University, Toyoake, Japan, 4Department of Radiology, Tokyo Metropolitan Health and Medical Treatment Corporation Ebara Hospital, Tokyo, Japan

IVIM analysis can provide the perfusion fraction f and the pseudodiffusion coefficient D* or Dp in addition to the diffusion parameters. The product of f and D* is known to relate to cerebral blood flow. Recently, a higher diagnostic performance of fD* than f and D* has been reported. We propose a method to estimate fDp without estimating f and Dp using DKI analysis. The DKI based IVIM analysis can be implemented easily and provides fDp values with a high degree of precision.

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