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Abstract #1590

IVIM D and f - Optimal estimation technique and their potential for tissue differentiation

Oscar Jalnefjord1,2, Mats Andersson3, Mikael Montelius1, Anna-Karin Elf4, Viktor Johanson4, Johanna Svensson5, Göran Starck1,2, and Maria Ljungberg1,2

1Department of Radiation Physics, University of Gothenburg, Gothenburg, Sweden, 2Department of Medical Physics and Biomedical Engineering, Sahlgrenska University Hospital, Gothenburg, Sweden, 3Department of Radiology, University of Gothenburg, Gothenburg, Sweden, 4Department of Surgery, University of Gothenburg, Gothenburg, Sweden, 5Department of Oncology, University of Gothenburg, Gothenburg, Sweden

IVIM parameter estimation restricted to D and f (avoiding D*) has gained increased popularity. In this study we show that the commonly used segmented fitting approach is preferable. We also show that differentiation between tumor and healthy liver tissue is substantially enhanced by the combined use of D and f.

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