Diffusion tensor imaging (DTI) is an imaging modality that detects the microstructural and pathological changes of organisms according to the diffusive characteristics of water molecules in the tissues. MR histogram analysis reflects the tumor heterogeneity. In the current study, histogram analysis of DTI was demonstrated to be capable to differentiate mass-forming cholangiocarcinoma and solitary hypovascular hepatic metastases, which can provide quantitative information for further clinical diagnosis.
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