Abstract #1603

Comparison of intravoxel incoherent motion DWI, diffusion kurtosis imaging, and conventional DWI in predicting the chemotherapeutic response of colorectal liver metastases: preliminary experience

Huan Zhang¹, Wenhua Li², Robert Grimm³, Caixia Fu⁴, Xu Yan⁵, and Tong Tong¹

¹Department of Radiology, Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China, ²Department of Medical Oncology, Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China, ³MR Application Predevelopment, Siemens Healthcare, Erlangen, Germany, ⁴APPL, Siemens Shenzhen Magnetic Resonance Ltd., Shenzhen, China, ⁵MR Collaboration NE Asia, Siemens Healthcare, Shanghai, China

The aim of this study was to compare the performance of pre-treatment intravoxel incoherent motion DWI (IVIM-DWI), diffusion kurtosis imaging (DKI), and conventional DWI for predicting the chemotherapeutic response in patients with colorectal liver metastases (CRLMs). The results indicates that they are all potentially useful for predicting the chemotherapeutic response of CRLMs, with mean diffusion derived from DKI having the best performance.

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