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Abstract #1603

Comparison of intravoxel incoherent motion DWI, diffusion kurtosis imaging, and conventional DWI in predicting the chemotherapeutic response of colorectal liver metastases: preliminary experience

Huan Zhang1, Wenhua Li2, Robert Grimm3, Caixia Fu4, Xu Yan5, and Tong Tong1

1Department of Radiology, Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China, 2Department of Medical Oncology, Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China, 3MR Application Predevelopment, Siemens Healthcare, Erlangen, Germany, 4APPL, Siemens Shenzhen Magnetic Resonance Ltd., Shenzhen, China, 5MR Collaboration NE Asia, Siemens Healthcare, Shanghai, China

The aim of this study was to compare the performance of pre-treatment intravoxel incoherent motion DWI (IVIM-DWI), diffusion kurtosis imaging (DKI), and conventional DWI for predicting the chemotherapeutic response in patients with colorectal liver metastases (CRLMs). The results indicates that they are all potentially useful for predicting the chemotherapeutic response of CRLMs, with mean diffusion derived from DKI having the best performance.

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Abstract