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Abstract #1621

Optimization of b values and reproducibility of perfusion and diffusion parameters using IntraVoxel Incoherent Motion (IVIM) with peripheral pulse triggering

Yu Ueda1, Minoru Hayashida2, Koji Yoshida2, Tomoyuki Okuaki1, Katsuyoshi Ito3, Makoto Obara1, and Marc Van Cauteren4

1Philips Japan, Tokyo, Japan, 2Kawasaki Medical School, Kurashiki, Japan, 3Yamaguchi University Graduate School of Medicine, Ube, Japan, 4Philips HealthTech, Tokyo, Japan

To investigate the reproducibility of IVIM-derived parameters with peripheral pulse unit (PPU) triggering and optimized b values combination to decrease scan time, we assessed the reproducibility by calculating coefficient of variation (CV) for each parameter. Moreover, D* and F calculated with some b value patterns were compared to those with all b values using the Pearson correlation. Our results suggest that cardiac gating does not improve reproducibility of perfusion and diffusion parameter. F with only 4 b values (e.g. b=0-200-500-1000) can provide robust information on perfusion noninvasively with significantly shortened scan time.

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