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Abstract #1626

Anisotropic Diffusion Filter for Simultaneous Combination and Denoising of Multiple Acquisitions in DWI of the Spinal Cord

Sevgi Gokce Kafali1,2, Cagri Aydinkarahaliloglu1, Tolga Çukur1,2, and Emine Ulku Saritas1,2

1Electrical and Electronics Engineering, Bilkent University, Ankara, Turkey, 2National Magnetic Resonance Research Center (UMRAM), Ankara, Turkey

In diffusion weighted imaging (DWI), multiple acquisitions are acquired and averaged to attain a reasonable SNR level, especially for high spatial resolution or high b-value imaging. However, bulk or involuntary physiological motion during diffusion-sensitizing gradients alters the k-space, creating unpredictable global and/or local phases across multiple acquisitions. Therefore, direct complex averaging of these multiple acquisitions is prohibited. Here, we propose a reconstruction scheme based on modified anisotropic diffusion filtering, which starts with complex-valued acquisitions and corrects the phase issues while improving the SNR. The proposed reconstruction is demonstrated with in vivo DWI of the cervical spinal cord at 1.5T.

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