Abstract #1633

Image-based Multi-Scale Distortion Correction: Application to Diffusion Imaging

Lars Bielak¹, Hatice Bunea², Nicole Wiedenmann², Anca-Ligia Grosu², and Michael Bock¹

¹Dept. of Radiology, Medical Physics, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany, ²Department of Radiation Oncology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, German Cancer Consortium (DKTK), Partner Site Freiburg, Freiburg, Germany

This work presents an algorithm that calculates a distortion field to correct a geometrically distorted image using an anatomically precise reference image. The algorithm employs mutual information based rigid image registration with a pyramidal architecture. Validation was performed on simulated distortion fields and in vivo comparison to a measured B₀-fieldmap.

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