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Abstract #1636

High-resolution off-resonance maps improve conformity between distortion-corrected EPI acquisitions and distortion-free references

Michael J van Rijssel1, Frank Zijlstra1, Peter R Seevinck1, Peter R Luijten1, Dennis W J Klomp1, and Josien P W Pluim1,2

1Center for Image Sciences, UMC Utrecht, Utrecht, Netherlands, 2Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, Netherlands

The majority of diffusion acquisitions is affected by geometrical distortions due to susceptibility induced off-resonance effects in the EPI readout. This hampers the use and effectiveness of these images in multiparametric cancer protocols, especially in lipid-rich environments such as the human breast where tissue interfaces cause large but local discontinuities. Preliminary results show that improvements upon existing correction techniques can be made by using high-resolution off-resonance information in distortion correction algorithms.

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