Intravoxel incoherent motion (IVIM) imaging employs a bi-exponential diffusion model to estimate capillary contributions to the diffusion-weighted signal. Major challenges of IVIM are long acquisition time, long processing time, and image distortion associated with EPI acquisition. In this work, we proposed a novel framework for rapid and distortion-free IVIM imaging called IVIM-Fingerprinting. It employs a single-shot acquisition scheme and an advanced image reconstruction scheme in combination with the recently proposed concept of MR Fingerprinting. Its performance was demonstrated both for simulation and for in-vivo studies.
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