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Abstract #1682

Diffusion-Weighted MR Imaging of the Parotid glands in healthy volunteers before and after a gustatory stimulation to quantify relative function

Matthew George Birkbeck 1, Fiona Elizabeth Smith1, and Andrew Matthew Blamire1

1Newcastle Magnetic Resonance Centre, Newcastle University, Newcastle upon Tyne, United Kingdom

Diffusion Weighted MR Imaging has been used to quantify the function of parotid glands. Clinically gland function is measured using Scintigraphy, but MR offers a non-invasive, non-ionising alternative to this method. A DWI sequence for investigating parotid gland function is presented and tested in five healthy volunteers scanned on two occasions. We used four parameters to represent gland function: perfusion fraction (fv), apparent perfusion coefficient (ADCperfusion), diffusion fraction (fd) and apparent diffusion coefficient (ADCdiffusion). Statistically significant changes were observed in fv, fd and ADCdiffusion in volunteers. Results indicate a normal range for these parameters.

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