Diffusion Weighted MR Imaging has been used to quantify the function of parotid
glands. Clinically gland function is measured using Scintigraphy, but MR offers
a non-invasive, non-ionising alternative to this method. A DWI sequence for
investigating parotid gland function is presented and tested in five healthy
volunteers scanned on two occasions. We used four parameters to represent gland
function: perfusion fraction (fv), apparent perfusion coefficient
(ADCperfusion), diffusion fraction (fd) and apparent
diffusion coefficient (ADCdiffusion). Statistically significant changes
were observed in fv, fd and ADCdiffusion in volunteers.
Results indicate a normal range for these parameters.