Abstract #1785

Paediatric brain tissue properties measured with magnetic resonance elastography

Jade Yeung¹, Lauriane Jugé ^1,2, and Lynne E. Bilston^1,3

¹Neuroscience Research Australia, Randwick, NSW, Australia, ²University of New South Wales, School of Medical Sciences, Kensington, NSW, Australia, ³University of New South Wales, Prince of Wales Clinical School, Kensington, NSW, Australia

Magnetic resonance (MR) elastography is a technique to noninvasively measure the mechanical properties of soft tissues. While adult brain data obtained with MR elastography is readily available, there is little data for healthy paediatric brains throughout development. MR elastography was performed on 25 healthy paediatric subjects aged between 7-18 years at three frequencies, and the shear moduli of white and grey matter were calculated and compared to data obtained from 10 healthy adults. The shear modulus of paediatric brains was not found to be age dependent, with no significant differences between adult and paediatric brains.

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