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Abstract #1824

A voxel-based diffusion kurtosis imaging study of whole-brain in chronic alcohol dependent patients

Hong-yan Nie1, Jun Chen1, Ya-qi Wang1, and Yang Fan2

1Department of Radiology, Renmin Hospital of Wuhan University, Wuhan, China, 2GE Healthcare China, Beijing, China

In the present study, diffusion kurtosis imaging (DKI), which is based on the method of voxel-based analysis(VBA), was used to investigate the alterations of microstructure of white matter and gray matter in chronic alcohol dependent patients. Thirty patients with chronic alcohol dependence and twenty healthy volunteers were scanned with DKI. Compared with the healthy control group, the brain regions associated with visual information processing, memory, movement coordination and emotional control capacity have been found to be abnormal in different degrees.

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