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Abstract #1872

Brain Cloud of Carbogen-based Cerebrovascular Reserve : territorial and cortical specificity

Tzu-chen Yeh1,2, Chou-ming Cheng3, and Chi-che Chou3

1Department of Radiology, Taipei Veterans General Hospital, Taipei, Taiwan, 2Institute of Brain Science, National Yang-ming University, Taipei, Taiwan, 3Integrated Brain Research Unit, Department of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan

To explore the spatial characters of carbogen-based cerebrovascular reserve (CO2-CVR), grouped analyses of CO2-CVR was obtained using BOLD-based fMRI for ninety normal subjects with the fully automatic delivery system of carbogens and parametric inhalation of 1-5% CO2. Distal territories of ACA, segment 3, showed the highest of CO2-CVR at v23ab (ventral portion of Brodmann area 23) as verified by territorial and cortical parcellation. Our findings supported the biological adapation of CVR for resting activity, e.g. default mode network.

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