Abstract #1887

Feasibility of cerebral blood volume mapping by using velocity selective arterial spin labeling with 3D radial gradient echo acquisition

Mulan Jen¹, James H Holmes², Patrick A Turski², and Kevin M Johnson^1,2

¹Department of Medical Physics, University of Wisconsin-Madison, Madison, WI, United States, ²Department of Radiology, University of Wisconsin-Madison, Madison, WI, United States

Theoretically, velocity selective arterial spin labeling (VS-ASL) can be utilized for obtaining cerebral blood volume (CBV). However, challenges such as large vessel contamination and readout dependent artifacts make it difficult to obtain quantitative values. This work investigates the feasibility of VS-ASL CBV mapping by using three-dimensional gradient echo radial acquisition. Measured CBV’s were found to be comparable to previous literature, however results highlight the potential resolution dependence of low SNR ASL based CBV mapping.

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