Abstract #1905

Language reorganization in pre-and post-operative drug refractory extra temporal lobe epilepsy patients: An fMRI based study

Kapil Chaudhary¹, Senthil Kumaran², Sarat P Chandra³, Ashima Nehra Wadhawan⁴, and Manjari Tripathi¹

¹Department of Neurology, All India Institute of Medical Sciences, New Delhi, India, ²Department of NMR and MRI Facility, All India Institute of Medical Sciences, New Delhi, India, ³Department of Neuro-Surgery, All India Institute of Medical Sciences, New Delhi, India, ⁴Department of Clinical Neuropsychology, All India Institute of Medical Sciences, New Delhi, India

Drug refractory epilepsy (DRE) patients have atypical language lateralization with ipsilateral and contra lateral hemispheric lesions and pathological abnormalities. Such kind of patients may have different language recovery after surgery. In this study, we have used a standardized Hindi-language paradigm using semantic, syntactic, judgement and comprehension components for testing in the North-Indian population. We observed greater improvement in language skills in ETLE-patients with correspondingly greater recruitment of the bilateral hemisphere.

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