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Abstract #1915

Noninvasive measurements of human brain temperature in patients with arteriovenous malformations using magnetic resonance spectroscopy

Takashi Inoue1, Tomohisa Ishida1, Shunsuke Omodaka2, Miki Fujimura2, Masayuki Ezura1, Hiroshi Uenohara1, and Teiji Tominaga3

1Neurosurgery, Sendai Medical Center, Sendai, Japan, 2Neurosurgery, Kohnan Hospital, Sendai, Japan, 3Neurosurgery, Tohoku University, Sendai, Japan

The present study investigated whether brain temperature measured by proton magnetic resonance (MR) spectroscopy can detect cerebral hemodynamic impairment in patients with arteriovenous malformations (AVMs) as shown by single photon emission computed tomography (SPECT). Brain temperature, cerebral blood flow, and cerebrovascular reactivity were measured using proton MR spectroscopy and SPECT in five healthy volunteers and six patients with AVMs. A significant correlation was observed between brain temperature difference (affected side - contralateral side) and cerebrovascular reactivity ratio (affected side/contralateral side) (r=0.82, p=0.0480). Brain temperature measured by proton MR spectroscopy can detect cerebral hemodynamic impairment in patients with AVMs.

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