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Abstract #1980

Sufficient Gradient Sampling for Diffusion Tensor Imaging in Clinical Trials

Ken Sakaie1, Jian Lin1, Josef Debbins2, Mark Lowe1, and Robert Fox3

1Imaging Institute, The Cleveland Clinic, Cleveland, OH, United States, 2Keller Center for Imaging Innovation, Barrow Neurological Institute, Phoenix, AZ, United States, 3Neurological Institute, The Cleveland Clinic, Cleveland, OH, United States

Although many diffusion-weighting gradients are desirable for diffusion MRI, implementation may be difficult in a multicenter trial for practical reasons. This study retrospectively examines the adequacy of using as few as 6 directions, the minimum required for calculating the diffusion tensor, for tissue microstructure measurements.

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