Abstract #1980

Sufficient Gradient Sampling for Diffusion Tensor Imaging in Clinical Trials

Ken Sakaie¹, Jian Lin¹, Josef Debbins², Mark Lowe¹, and Robert Fox³

¹Imaging Institute, The Cleveland Clinic, Cleveland, OH, United States, ²Keller Center for Imaging Innovation, Barrow Neurological Institute, Phoenix, AZ, United States, ³Neurological Institute, The Cleveland Clinic, Cleveland, OH, United States

Although many diffusion-weighting gradients are desirable for diffusion MRI, implementation may be difficult in a multicenter trial for practical reasons. This study retrospectively examines the adequacy of using as few as 6 directions, the minimum required for calculating the diffusion tensor, for tissue microstructure measurements.

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