Meeting Banner
Abstract #2021

Increased Mode of Anisotropy in crossing-fibre areas predicts conversion from Mild Cognitive Impairment (MCI) to Alzheimer's disease (AD)

Matt C Gabel1, Meena Zaveri2, Laura Serra3, Marco Bozzali1,3, and Mara Cercignani1

1Clinical Imaging Sciences Centre, Brighton and Sussex Medical School, Brighton, United Kingdom, 2School of Life Sciences, University of Sussex, Falmer, United Kingdom, 3Neuroimaging Laboratory, Santa Lucia Foundation IRCCS, Rome, Italy

Diffusion MRI was used to examine whether any change in the white matter tracts of patients with mild cognitive impairment (MCI) can predict conversion to Alzheimer’s disease (AD) in a longitudinal study. Our data show increases in mode of anisotropy (MO) in a region of crossing fibres in the centrum semiovale for MCI patients who later converted to AD.

This abstract and the presentation materials are available to members only; a login is required.

Join Here