Abstract #2049

A Simplified Method to Estimate Perfusion Characteristics of Gliomas based on Diffusion-weighted Imaging

Mengqiu Cao¹, Shiteng Suo¹, Xu Han¹, Yawen Sun¹, Yao Wang¹, Weina Ding¹, Ke Jin², Xiaohua Zhang², Jianxun Qu³, and Yan Zhou¹

¹Department of Radiology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, P.R. China, Shanghai, China, ²Department of Neurosurgery, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, P.R. China, Shanghai, China, ³GE Healthcare China, Shanghai, P.R. China, Shanghai, China

The purpose of the study was to evaluate the application of a simplified method to estimate the perfusion characteristics of glioma as an alternative less time-consuming approach. Fifty patients confirmed with glioma were assessed with multi-b-value DWI and DCE MR imaging. Results indicated that the simplified perfusion fraction (SPF) based on DWI acquired with three b-values showed strong correlation with IVIM-derived f and D*, and showed medium correlation with DCE MR imaging-derived Ktrans and vp. SPF achieved the highest accuracy for gliomas grading. SPF may serve as a valuable alternative to measure tumor perfusion in gliomas.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.