Abstract #2072

Differentiation and Quantification of White Matter Injury in Post-Hemorrhagic Hydrocephalus

Albert M. Isaacs¹, Harri Merisaari², Tsen-Hsuan Abby Lin², James (Pat) James McAllister³, David D Limbrick³, and Sheng-Kwei (Victor) Song²

¹Neuroscience, Washington University School of Medicine, St. Louis, MO, United States, ²Radiology, Washington University School of Medicine, St. Louis, MO, United States, ³Neurosurgery, Washington University School of Medicine, St. Louis, MO, United States

This study is the first of its kind, and uses diffusion basis spectrum imaging (DBSI) to quantify, as well as differentiate the complex pathologies that underlies the white matter injury in post-hemorrhagic hydrocephalus (PHH) in neonates, using a ferret model of PHH.

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