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Abstract #2080

Integration and segregation of functional segmented anterior and posterior hippocampal networks in memory performance

Jingjing Xu1, Xiaojun Guan1, Xiaojun Xu1, and Minming Zhang1

1Radiology, the Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, China

In this study, we used a novel functional segmentation method to subdivided the left and right hippocampus into anterior and posterior portions according to preferred functional connections with certain cortical regions. And we investigated the association between specific performance of verbal and visual memories and intra-hemispheric resting state FC across anterior and posterior hippocampal networks using resting functional MRI measures in healthy young volunteers. The present results demonstrated that, the anterior hippocampus was specifically involved in the visual memory processing, whereas the posterior hippocampus contributed to both the verbal and visual memories, which may have implications for a functionally synergetic and dissociable role of the hippocampus in different kinds of memory.

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