The aim of this study is to determine whether the distribution pattern of intratumoral susceptibility sign (ITSS) derived from susceptibility-weighted imaging (SWI) could differentiate glioblastoma multiforme (GBM) and single brain metastasis. We compared the grade of the visibility of ITSS in the central portion of tumors (CITSS) and in the tumor capsular area (PITSS) on SWI. Our findings suggest that there were different characteristics of ITSS between GBM and brain metastasis on SWI due to the profound difference in histologic feature of capillary between the two tumor types.
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