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Abstract #2167

Measurement of Pulmonary Perfusion using PCASL True-FISP Imaging at 1.5 Tesla

Petros Martirosian1, Ferdinand Seith2, Rolf Pohmann3, Martin Schwartz1,4, Thomas Küstner1,4, Klaus Scheffler3,5, Konstantin Nikolaou2, and Fritz Schick1

1Section on Experimental Radiology, University of Tübingen, Tübingen, Germany, 2Department of Diagnostic and Interventional Radiology, University of Tübingen, Tübingen, Germany, 3Max Planck Institute for Biological Cybernetics, Tübingen, Germany, Tübingen, Germany, 4Institute of Signal Processing and System Theory, University of Stuttgart, Stuttgart, Germany, 5Department of Biomedical Magnetic Resonance, University of Tübingen, Tübingen, Germany

Pseudo-continuous-arterial-spin-labeling (PCASL) has been successfully applied in the liver and kidney providing high signal-to-noise-ratio. The goal of this work is to assess the potential of PCASL technique to measure the pulmonary perfusion at 1.5 T. Effective labeling of pulmonary blood flow was achieved by ECG triggering and an orientation of the labeling plane perpendicular to the pulmonary trunk. Fast True-FISP imaging with short TE of 0.9 ms was used to obtain high signal from lung parenchyma. The PCASL-True-FISP technique provides high quality perfusion images of the lung and allows quantitative measurements of pulmonary perfusion both in multiple breath-holds and under free breathing condition.

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