Abstract #2195

Simultaneous quantification of fat fraction, susceptibility and R2* from a single GRE acquisition: flip-angle effects

Junmin Liu¹, Spencer Christiansen^1,2, and Maria Drangova^1,2

¹Imaging Research Laboratories, Robarts Research Institute, Schulich School of Medicine & Dentistry, University of Western Ontario, London, ON, Canada, ²Medical Biophysics, Schulich School of Medicine & Dentistry, University of Western Ontario, London, ON, Canada

We report on a systematic investigation of the flip-angle (FA) effects on the quantification of fat fraction (FF), susceptibility, and R2* simultaneously from a single multi-echo GRE (mGRE) acquisition. Using a phantom with a range of oil-water emulsions and aqueous Gadolinium solutions we tested five different FAs (1°, 3°, 5°, 8° and 15°) with a bipolar mGRE protocol and were able to successfully generate the FF, susceptibility and R2* maps for all cases. Our results demonstrate that a single mGRE scan with optimized TEs has the potential to accurately measure quantitative FF, susceptibility, and R2* with a FA of 8°.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.