Abstract #2219

Reproducibility of Quantitative Susceptibility Mapping and R2* Mapping of the Human Brain at 7T: a Multi-Centre Pilot Study

Catarina Rua¹, William T Clarke², Ian D Driver³, Olivier Mougin⁴, Stuart Clare², Susan Francis⁴, Keith Muir⁵, Richard Wise³, Guy Williams¹, Richard Bowtell⁴, and Adrian Carpenter¹

¹Department of Clinical Neurosciences, University of Cambridge, Wolfson Brain Imaging Centre, Cambridge, United Kingdom, ²University of Oxford, Welcome Centre for Integrative Neuroimaging (FMRIB), Oxford, United Kingdom, ³School of Psychology, Cardiff University, Cardiff University Brain Research Imaging Centre, Cardiff, United Kingdom, ⁴University of Nottingham, Sir Peter Mansfield Imaging Centre, Nottingham, United Kingdom, ⁵University of Glasgow, Institute of Neuroscience & Psychology, Glasgow, United Kingdom

To perform cost-effective research with high-field imaging by increasing the size of the patient pool in investigations of brain diseases, it is important to guarantee cross-site reproducibility and consistency of the QSM and R2* results. This study is part of a pilot “travelling-heads” experiment from the UK7T network, in which we aim to develop harmonized approaches for T2*-weighted imaging in order to provide a framework for future multi-centre clinical studies at 7T.

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