The chemical exchange saturation transfer (CEST) MRI usually requires long RF irradiation before every data acquisition to achieve the steady-state CEST mechanism. To eliminate the repeatedly required RF irradiations and to increase the scan efficiency, a new CEST MRI technique that performs the RF irradiation in parallel with data acquisition is developed. The results of MR experiments demonstrate the feasibility of the proposed technique in amide proton CEST.
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