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Abstract #2238

In vivo imaging of Nucleus of the solitary tract at ultra-high field: a preliminary study

Nikos Priovoulos1, Benedikt A Poser2, Roberta Sclocco3,4, Vitaly Napadow3,4,5, Frans Verhey1, and Heidi IL Jacobs1,2,6

1Alzheimer Center Limburg, Maastricht University, Maastricht, Netherlands, 2Department of Cognitive Neuroscience, Maastricht University, Maastricht, Netherlands, 3Department of Radiology, Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Boston, MA, United States, 4Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, United States, 5Department of Radiology, Logan University, Chesterfield, MT, United States, 6Department of Radiology, Division of Nuclear Medicine and Molecular Imaging, Harvard Medical School, Boston, MA, United States

The nucleus of the solitary tract consists of a set of nuclei in medulla oblongata involved in several homeostatic systems. No method has been proposed so far to image it in vivo, due to its low contrast with standard T1 and T2-weighted methods, its small size and its position deep in the medulla. In this study we present preliminary results that indicate that NTS may be sensitive to magnetization transfer effects.

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