Abstract #2254

Evaluation of A Method for Simultaneous in vivo Measurements of Blood T1 and T2

Jialu Zhang^1,2,3, Dingxin Wang³, Xiaotong Zhang^1,2, Lynn E. Eberly ⁴, Gregory J. Metzger³, Donald R. Dengel⁵, David Tupper⁶, Anne M. Murray⁷, and Xiufeng Li³

¹Interdisciplinary Institute of Neuroscience and Technology, Qiushi Academy for Advanced Studies, Zhejiang University, Hangzhou, China, ²College of Biomedical Engineering & Instrument Science, Zhejiang University, Hangzhou, China, ³Center for Magnetic Resonance Research, School of Medicine, University of Minnesota, Minneapolis, MN, United States, ⁴Division of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, MN, United States, ⁵Laboratory of Integrative Human Physiology, School of Kinesiology, University of Minnesota, Minneapolis, MN, United States, ⁶Neuropsychology Section, Hennepin County Medical Center, Minneapolis, MN, United States, ⁷Berman Center for Clinical Research, Hennepin County Medical Center, Minneapolis, MN, United States

The longitudinal and transverse relaxation time constants of blood are important parameters for MRI methods and biomedical research studies. However, these parameters can vary largely across subjects, and change significantly across developmental stages, with physiological states, and due to specific diseases, which has motivated in vivo measurements of these parameters. We implemented a fast method for simultaneous in vivo measurements of blood T₁ and T₂. The study results suggest that the in vivo measurements of blood T₁ and T₂ can be achieved in about 25 s using the implemented method.

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