Synthetic MRI (SyMRI) provides quantitative PD, T1 and T2 maps via a rapid single-volume acquisition. Here, we aim to validate the precision and accuracy of SyMRI quantification by performing five scan re-scans, at two field strengths, of the quantitative NIST phantom and one control subject. Results show a good accuracy of T1 and T2 quantification at 3T, and a very good precision of all the phantom and subject measurements at 1.5T and 3T (95% confidence intervals width are respectively lower than 6% and 4%, of the measured value). This study brings confidence in comparing SyMRI quantitative measurements across subjects or time.
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