Abstract #2280

Accuracy and precision of Synthetic MRI

Gabriel Mangeat¹, Russell Ouellette^2,3, Marcel Warntjes^4,5, Michael Plattén^2,3, Love Engström Nordin^6,7, Nikola Stikov^1,8, Tobias Granberg^2,3, and Julien Cohen-Adad^1,9

¹NeuroPoly Lab, Institute of Biomedical Engineering, Polytechnique Montreal, Montreal, QC, Canada, ²Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden, ³Division of Neuroradiology, Department of Radiology, Karolinska University Hospital, Stockholm, Sweden, ⁴Center for Medical Imaging Science and Visualization, CMIV, Linköping, Sweden, ⁵SyntheticMR, Linköping, Sweden, ⁶Department of Diagnostic Medical Physics, Karolinska University Hospital, Stockholm, Sweden, ⁷Division of Clinical Geriatrics, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden, ⁸Montreal Health Institute, Montreal, QC, Canada, ⁹Functional Neuroimaging Unit, CRIUGM, Université de Montréal, Montreal, QC, Canada

Synthetic MRI (SyMRI) provides quantitative PD, T1 and T2 maps via a rapid single-volume acquisition. Here, we aim to validate the precision and accuracy of SyMRI quantification by performing five scan re-scans, at two field strengths, of the quantitative NIST phantom and one control subject. Results show a good accuracy of T1 and T2 quantification at 3T, and a very good precision of all the phantom and subject measurements at 1.5T and 3T (95% confidence intervals width are respectively lower than 6% and 4%, of the measured value). This study brings confidence in comparing SyMRI quantitative measurements across subjects or time.

This abstract and the presentation materials are available to members only; a login is required.

Join Here