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Abstract #2283

Can the slow compression wave in MRE data be inverted? An exploratory analysis

Eric Barnhill1, Jürgen Braun2, and Ingolf Sack1

1Radiology, Charité, Berlin, Germany, 2Medical Informatics, Charité, Berlin, Germany

Magnetic Resonance Elastography (MRE) data show high-amplitude, low frequency artifact which does not accord with the viscoelastic model in near-incompressible tissue. This exploratory study investigates whether the low frequency behavior is poroelastic, and if so whether slow compression wavelengths can be estimated. A cohort of abdominal MRE acquisitions at four frequencies were convolved with a fine-grained Gabor filter bank, and the frequency response of the acquisitions were pooled across subjects for liver and spleen regions. The pooled frequency responses for both liver and spleen showed a shifting peak in the response function mass that tracked with the increase in frequency, with wavespeeds in the shear regime. A second peak identified a lower frequency regime. This regime produced values similar to those observed in tissue poroelastic behaviors.

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