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Abstract #2285

Wideband mechanical tests of the viscoelastic powerlaw behavior of phantom materials for Magnetic resonance elastography

Felix Schrank1, Heiko Tzschätzsch1, Angela Ariza de Schellenberger1, Paul Janmey2, Jürgen Braun3, and Ingolf Sack1

1Department of Radiology, Charité - Universitätsmedizin Berlin, Berlin, Germany, 2Institute for Medicine and Engineering, University of Pennsylvania, Philadelphia, PA, United States, 3Institute of Medical Informatics, Charité - Universitätsmedizin Berlin, Berlin, Germany

Shear rheometry was combined with magnetic resonance elastography (MRE) in a 1.5-T clinical system and a 0.5-T tabletop MRE system to investigate the viscoelastic powerlaw behavior of heparin and polyacrylamide (PAAm) over more than three orders of magnitude dynamic range. While heparin has softer properties than encountered in soft in-vivo tissues, crosslinked PAAm has similar stiffness as measured for in-vivo tissues, however, with lower dispersive properties. Overall both materials are good candidates for the use as standard phantom materials in MRE due to their well predictable springpot properties across the full frequency range relevant for MRE investigations.

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