Abstract #2354

Changes in functional connectivity in the ventral attention system

Louis Gudmundsson ^1,2, Jakub Vohryzek¹, Eleonora Fornari³, Stephanie Clarke², Patric Hagmann¹, and Sonia Crottaz-Herbette²

¹Department of Radiology, Centre Hospitalier Universitaire Vaudois (CHUV), and University of Lausanne, 1011 Lausanne, Switzerland, Unil, Lausanne, Switzerland, ²Neuropsychology and Neurorehabilitation Service, Centre Hospitalier Universitaire Vaudois (CHUV), and University of Lausanne, 1011 Lausanne, Switzerland, Unil, Lausanne, Switzerland, ³CIBM (Centre d'Imagerie Biomédicale), Dept. of Radiology, Centre Hospitalier Universitaire Vaudois (CHUV), and University of Lausanne, 1011 Lausanne, Switzerland, Unil, Lausanne, Switzerland

Prismatic adaptation (PA), a therapy for neglect after a stroke, showed conflicting results in the literature. The variability of brain lesions leading to neglect and their relation to structures affected by PA could explain those results. MRI studies found focal brain activations after PA. We aim to understand if there is an effect on functional networks after PA. To do so, we analyzed the resting state fMRI connectivity of healthy subjects before and after PA. We found that the ventral attention system (VAS) was less connected after PA, this provides new insights to select patients for this therapy.

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