Abstract #2369

Assessing cue-induced brain response in heroin-dependents treated by methadone maintenance and protracted abstinence measures

Xuan Wei¹, Jiajie Chen², Qiang Li³, Wei Li², and Wei Wang³

¹Department of Radiology, Tangdu Hospital, The Fourth Military Medical University, Xi'an, China, ²radiology department of Tangdu hospital, The Fourth Military Medical University, Xi’an, China, ³Radiology department of Tangdu hospital, The Fourth Military Medical University, Xi’an, China

Our research aimed to compare PA with MMT,to reveal which abstinence way is better to recover the brain function in heroin-dependent individuals.24 heroin-dependent patients under PA ,19 heroin-dependent patients under MMT and 20 healthy volunteers were recruited. The functional images were acquired by using a spin-echo EPI. In the last part of this study, we proved PA group is closer to healthy group.This study showed that PA is more advantageous than MMT to reduce heroin addiction in drug cue-reactivity.

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