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Abstract #2404

Correcting for erroneous assessment of resting-state functional connectivity caused by prolonged arterial arrival time: a study in Moyamoya patients

Hesamoddin Jahanian1, Thomas Christen2, Michael Moseley2, and Greg Zaharchuk2

1Radiology, University of Washington, Seattle, WA, United States, 2Radiology, Stanford University, Palo Alto, CA, United States

We studied the default mode network in a group of Moyamoya patients using ICA method and observed erroneous assessments of functional connectivity in regions with prolonged arterial arrival time. We showed that these arterial delays could lead to erroneous elimination of affected brain regions from a functional connectivity network. We proposed a method called “temporal realignment” to mitigate this problem.

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