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Abstract #2450

A Subspace Approach to Accelerated HASTE Acquisition for Fetal Brain MRI

Bo Zhao1,2, Borjan Gagoski2,3, Justin P. Haldar4, Elfar Adalsteinsson5, Ellen Grant3,6, and Lawrence L. Wald1,2

1Athinoula A. Martinos Center for Biomedical Imaging, Chalestown, MA, United States, 2Harvard Medical School, Boston, MA, United States, 3Boston Children's Hospital, Boston, MA, United States, 4Electrical Engineering, University of Southern California, Los Angeles, CA, United States, 5Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA, United States, 6Radiology, Harvard Medical School, Boston, MA, United States

HAlf-fourier Single-shot Turbo spin Echo (HASTE) acquisition is widely used in fetal MR imaging due to its T2 contrast and motion robustness, but speed and T2-blurring remain a problem for fully sampled acquisitions. In the work, we describe a new reconstruction approach based on low-rank and subspace modeling of local k-space neighborhood to accelerate HASTE acquisition. The proposed approach decreases the echo-train length with improved image quality and noise robustness compared to conventional reconstruction. It is compatible with the vendor-provided acquisition. The effectiveness and utility of the proposed approach is evaluated with both retrospectively and prospectively undersampled fetal imaging data.

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