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Abstract #2454

Extraction of fractional ventilation from dynamic oxygen enhanced MRI experiments: preliminary results

Marta Tibiletti1, Jose Ulloa1,2, and Geoff JM Parker1,2

1Bioxydyn Ltd, Manchester, United Kingdom, 2Centre for Imaging Sciences, University of Manchester, Manchester, United Kingdom

Fractional ventilation (FV) weighted maps were extracted from free-breathing dynamic O2 enhanced (dynOE) experiment in cystic fibrosis patients. FV is related to the local expansion of the tissue due to gas arrival in inspiration, while dynOE maps the local rate of the arrival of O2 and the maximum enhancement obtained. These parameters can be extracted from the same acquisition, providing complementary information regarding local lung function.

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