Abstract #2494

Application of T1rho and T1 mapping MRI in Tracking Renal Ischemia Reperfusion Injury Process in Rats

Yangguang Yuan^1,2, Jingjing Huang¹, Yingjie Mei³, Siying Wang⁴, and Wen Liang¹

¹Medical Image Center, Zhujiang Hospital, Southern Medical University, Guangzhou, China, ²Radiology Department, Shenzhen Luohu People’s Hospital, Shenzhen, China, ³Philips Healthcare, Guangzhou, China, ⁴Philips Healthcare, Shanghai, China

Previous studies using T1rho and T1 mapping in the liver and heart demonstrated that T1rho value and T1 relaxation time can be used to assess acute injury and long-term tissue fibrosis1. However, to the best of our knowledge, these techniques have not been explored to evaluate acute kidney ischemia damage. In our study, we found that T1rho value and T1 relaxation time showed high specificity and sensitivity in a rat renal ischemia reperfusion injury (IRI) model.

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