Abstract #2516

Evaluation of fibrosis models using 1H T1 mapping and 23Na T2*.

Per Mose Nielsen¹, Christian Østergaard Mariager², Christoffer Mose Laustsen¹, Marie Mose Mølmer², and Rikke Nørregaard²

¹MR Research Center, Clinical Institute, Århus N, Denmark, ²Clinical Institute, Århus N, Denmark

In this study we try to develop a renal IRI model which leads to fibrosis. Fibrosis markers indicate the best effect after 7 days of reperfusion. We also investigate the possibility of using 23Na T2* to evaluate fibrosis, this gave rise to a correlation with fibrosis markers only when normalizing to water transport from cortex to medulla.

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