This study was designed to investigate the signal intensities (SI) of abdominal organs on pre- and post-enhanced HASTE images using ferumoxytol at a dose of 4mg /kg, and to compare the differences of enhancement effect among the organs. We found that the SI of liver, spleen, and pancreas were significantly decreased on HASTE after ferumoxytol administration. The greatest effects on SI were observed in liver and spleen. Little change in SI of muscle and fat was noted. The findings suggest that normal liver and spleen undergo profound decrease in signal intensity following ferumoxytol injection, likely reflecting their high blood volume. This observation suggests a potential role for ferumoxytol in detection and characterization of focal lesions of the liver and spleen.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords