Abstract #2565

Multi parametric magnetic resonance imaging for the detection of prostate cancer: combination of T2-weighted, diffusion tensor imaging and magnetic resonance spectroscopic imaging

Neda Gholizadeh¹, Peter B Greer^2,3, John Simpson^2,3, Jim Denham⁴, Peter Lau^5,6, and Saadallah Ramadan^1,6

¹Health Science, The University of Newcastle, Newcastle, Australia, ²Radiation oncology, Calvary Mater Newcastle, Newcastle, Australia, ³Medical Physics, The University of Newcastle, Newcastle, Australia, ⁴Radiation oncology, calvary mater newcastle, Newcastle, Australia, ⁵Radiology, Calvary Mater Newcastle, Newcastle, Australia, ⁶Imaging Centre, Hunter Medical Research Institute (HMRI), Newcastle, Australia

The aim of this study was to determine the diagnostic performance of mp-MRI using T2WI, DWI, DTI and MRSI for prostate cancer patients with various Gleason scores. mp-MRI using T2WI, DWI, DTI and MRSI on 12 prostate cancer patients. The area under receiver operating characteristic (ROC) curve of T2WI+DWI and T2WI+DWI+DTI+MRSI images were generated and used to evaluate the performance of mp-MRI for discriminating cancer and healthy regions. Our results suggest that mp-MRI using DWI, DTI and MRSI in combination with structural T2WI improve performance for discrimination of cancer and healthy prostate tissues.

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