We report the results of the pilot study carried out using multiparametric (mp) MRI and in-bore MRI-guided prostate biopsy for detection of PCa to reduce the number of unnecessary biopsies. 11 patients were recruited based on prostate specific antigen > 4ng/ml and abnormal digital rectal examination. In-bore MRI targeted lesions with high PIRADS scores (3 to 5) were correlated with the histopathological findings. The average ADC in PCa patients was significantly lower than the prostatitis and BPH patients. Out of 11 patients, 3 showed adenocarcinoma, 5 prostatitis and 3 BPH.