The aim of this study was to determine the most accurate weighting factor for precise quantification of fatty liver when the 6-point interference Dixon fat percentage imaging technique is used by analyzing changes in WFs of fatty acid metabolites in liver. The importance of accurate WFs in the calculation of 6-pt-DIXON-based FP was confirmed in the phantom experiment. This study proposes average WF values that can be effectively used to acquire accurate 6-pt-DIXON FP images for non-alcoholic fatty liver. In addition, if the WFs of liver parenchyma FMs are applied, the accuracy of 6-pt-DIXON FP imaging can further increase.
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