Primary sclerosing cholangitis (PSC) is a chronic liver disease characterized by heterogeneous distribution of increased stiffness in periphery, segmental or lobar pattern. The heterogeneity of liver stiffness has raised concerns for reproducibility of liver stiffness measurement (LSM). We performed interobserver agreement analysis for LSM with two readers drawing manual regions of interest (ROI) and with an automated algorithm. Our study results show that large geographical ROIs including the focal regions of increased liver stiffnesses have excellent agreement between readers and automated method. Therefore large geographical ROIs using either manual or automated methods should be used for LSM in PSC patients.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords