Abstract #2608

Test-retest Repeatability of R2* Mapping and Quantitative Susceptibility Mapping for Liver Iron Quantification

Ante Zhu^1,2, Timothy J. Colgan², Scott B. Reeder^1,2,3,4,5, and Diego Hernando^2,3

¹Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, United States, ²Radiology, University of Wisconsin-Madison, Madison, WI, United States, ³Medical Physics, University of Wisconsin-Madison, Madison, WI, United States, ⁴Medicine, University of Wisconsin-Madison, Madison, WI, United States, ⁵Emergency Medicine, University of Wisconsin-Madison, Madison, WI, United States

Liver iron concentration is widely recognized as the best overall metric of total body iron content. Accurate and precise (repeatable) non-invasive measurements of liver iron concentration are needed. In this work, we assessed the test-retest repeatability of R2* mapping and quantitative susceptibility mapping (QSM) in patients with liver iron overload at 1.5T. Our test-retest measurements demonstrate good agreement in different protocols for R2* quantification but large limits of agreements for QSM susceptibility estimates. Further optimization of QSM techniques is needed to improve test-retest repeatability.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.