We calculated the hepatocytefraction (Hep) and reduction rate of T1 relaxation time (RE) based on T1changes in the hepatocyte due to pharmacokinetics of gadoliniumethoxybenzyl-diethylenetriamine pentaacetic acid (Gd-EOB-DTPA) uptake in liver.Both Hep and RE were compared with liver fibrosis stage according to theMETAVIR scoring system. And we found that Hep significantly correlated withfibrosis stage, and indicate it a good quantitative biomarker for liver fibrosis estimation.
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