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Abstract #2614

More than Hepatobiliary Relative Enhancement Ratio by Gd-EOB-DTPA for Liver Fibrosis Estimation, Hepatocyte Fraction method by T1 mapping measurement

Shen Pan1, Xiaoqi Wang2, and Qiyong Guo1

1Sheng Jing Hospital, Shenyang, China, 2Philips Healthcare, Beijing, China

We calculated the hepatocytefraction (Hep) and reduction rate of T1 relaxation time (RE) based on T1changes in the hepatocyte due to pharmacokinetics of gadoliniumethoxybenzyl-diethylenetriamine pentaacetic acid (Gd-EOB-DTPA) uptake in liver.Both Hep and RE were compared with liver fibrosis stage according to theMETAVIR scoring system. And we found that Hep significantly correlated withfibrosis stage, and indicate it a good quantitative biomarker for liver fibrosis estimation.

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